I would like to order more than one test on a patient. Do I need to fill in more than one request form?

No, different tests can be ordered for one patient.

I would like to order another test on a patient who was tested previously. Do I need to submit another specimen?

No. Generally, Amsterdam GenomeDx obtains enough DNA from one specimen to allow completion of a number of tests. A second specimen is not necessary, when requested within 5 years.

What is the procedure for adding on further testing to a sample already at Amsterdam GenomeDx?

An additional test can be added on to a sample already at Amsterdam GenomeDx by submitting a new order form for the new test to be performed. Please reference the Amsterdam GenomeDx lab number, patient’s name and date of birth.

When can I expect the test results?

Our goal is to provide you with an accurate result in a reasonable time period. The majority of our tests takes approximately 6-8 weeks to complete. Analysis of NGS-panels can take longer, due to the higher number of genes analysed and the complexity of the interpretation. The time it takes to complete a test varies depending on a number of factors. The size of the gene, the complexity of the interpretation, the occasional need to redesign or repeat a test, and other factors can increase the turn around time. Testing can take from 2-10 weeks depending on which genetic test was ordered. The information tag for each condition (see Test catalog) indicates an estimated time frame for completion of the test. These estimates are based on the average amount of time it has taken us to complete the test in the past. As soon as a test is completed the results are mailed to the referring physician or ordering facility. Prenatal testing usually takes 2-3 weeks and test results can be communicated by phone, fax or email according to the physician’s preference.

The test result has been lost or was never received, can you resend it?

Amsterdam GenomeDx can provide you with a duplicate copy of the test result if you are the ordering physician or are from the ordering facility. We cannot send results to the patient or other physicians involved in the care of the patient without a signed release from the patient authorizing us to do so.

Can a test be expedited?

All prenatal tests are expedited.  Other common indications for expediting a test in the lab are a scheduled or necessary procedure (e.g. surgery) and  follow up treatment. If there are other medical indications for expediting a test, please let us know and we will do our best to get a result out as quickly as possible. Please note that for all expedited tests an extra charge of € 240 will be applied.

How is billing done?

An invoice will be sent to the ordering physician’s address or to the address indicated on the test requisition form. Please pay within 30 days by bank money transfer to the bank account nr. indicated on the invoice. Please always refer to the Request No. (see order form).

Where do I send a specimen?

Amsterdam GenomeDx
Amsterdam UMC
Dept. Clinical Genetics, L01-158
Meibergdreef 9
1105 AZ AMSTERDAM – The Netherlands

How do I send a specimen?

A specimen should be packed in materials that prevent its container from being damaged during shipment. Specimen tubes should be labeled with patient name and date of birth. Unlableled specimen tubes will be rejected by Amsterdam GenomeDx. DNA and buccal swabs specimens can be sent through the regular postal mail. Blood can also be sent through regular mail, provided that the shipment does not take longer than 4-5 days. Prenatal specimens should be shipped to us using an express delivery service.  All specimens should be shipped to us with a completed requisition form. For more information visit our Specimen Requirements page or contac us.

Does Amsterdam GenomeDx pay for shipping?

No, the cost of shipping is the responsibility of the sender.

I am drawing a specimen from an infant. What is the minimum amount of blood required?

For infants, we would like 5-10 ml whole blood in EDTA (purple top tube) to perform any test.

Do you accept buccal swabs specimens?

We do accept buccal swabs specimens under special circumstances. For nearly all of our tests, the quality of DNA obtained from a buccal swab specimen is not sufficient to complete the testing ordered. We actually prefer blood specimens for all our tests. Please contact us to check whether buccal swabs can be used for the test you wish to order.

If more than one test is being ordered on the same patient, is it better to provide a tube of blood for each test?

No. Amsterdam GenomeDx obtains enough DNA from one specimen to complete a number of tests. Unused DNA material is stored for prolonged periods of time, unless we receive specific instruction to send the material back or to destroy it. For further details please contact us .

What are the specimen requirements for prenatal testing?

The following specimens are necessary for completion of a prenatal test:

• Maternal blood (1-4 ml in a purple-top EDTA tube) is required for maternal cell contamination (MCC) studies. The maternal sample should accompany the prenatal specimen or be shipped to arrive prior to or concurrently with the prenatal sample.
• Maternal and Paternal blood is required for prenatal array testing.
• If one prenatal test is ordered, one of the following is required: 10-15 ml of Amniotic fluid, 30 mg of Chorionic villi, min. 1 T25 flasks of cultured amniocytes or cultured chorionic villi. If more than one prenatal test is being ordered on a specimen, one of the following is required: 30 ml of Amniotic fluid, 30 mg of Chorionic villi, 3 T25 flasks of cultured amniocytes or cultured chorionic villi. Please note that orders for prenatal diagnostics will be accepted only upon notification to our office.

Can I send DNA?

Yes. Please send a minimum volume of 20 µl and minimum concentration of 50 ng/µl (50 µg/ml). For testing on a single exon, we require 1-2 ug of DNA. If we are testing 2-10 exons, we require 5-10 ug and for tests with more than 10 exons, we need 20 ug.

How do I use this website to order a test?

Follow these step-by-step instructions:

1. Search for a gene, disorder or test on the homepage or test catalog page
2. In the list of results, click the name of a single gene test or NGS panel to add it to your selection. The My selection button displays the number of selected tests and gives access to the summary and details of your test selection
3. After selecting all required tests, click the Order test button under My selection
4. Complete the electronic order form. Mandatory fields are marked with an asterisk (*)
5. When submitting an order (i.e. clicking ‘Submit’ at the bottom of the electronic order form) a confirmation email will be sent to the Ordering physician email address indicated in the form, and a printable version of your order will be available in the confirmation window
6. Print the form as instructed and add it to your sample (manually complete the pedigree if applicable)
7. Send your sample to the Shipping address indicated in Shipping

Do I have to register for an account?

Registration is optional, you can submit a test order without registration. Registration is advised for recurrent users, as your account profile information, such as ordering physician and billing information, will be used to automatically complete parts of the order form.